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Artikel Thrombozytopenien: Literatur

Autor/en: A. Matzdorff
Letzte Änderung: 15.03.2011
  • Ahn YS, Byrnes JJ, Harrington WJ, Cayer ML, Smith DS, Brunskill DE, Pall LM.
    The treatment of idiopathic thrombocytopenia with vinblastine-loaded platelets.
    N Engl J Med 1978;298:1101-1107. PMID:565464

  • Alimardani G, Guichard J, Fichelson S, Cramer EM.
    Pathogenic effects of anti-glycoprotein Ib antibodies on megakaryocytes and platelets.
    Thromb Haemost 2002;88:1039-1046. PMID: 12529757

  • AMGEN.
    Rote-Hand-Brief: Nplate® (Romiplostim) - Überarbeitete Dosisanpassung bei Patienten mit ITP und Warnhinweise für die Anwendung bei ITP-Patienten mit Leberfunktionsstörung.
    AMGEN München 15.12.2010

  • Andersen JC.
    Response of resistant idiopathic thrombocytopenic purpura to pulsed high-dose dexamethasone therapy.
    N Engl J Med 1994;330:1560-1564. PMID:8177245

  • Arnold DM, Bernotas A, Nazi I, Stasi R, Kuwana M, Liu Y, Kelton JG, Crowther MA.
    Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection: a systematic review.
    Haematologica 2009;94:850-856. PMID: 19483158

  • Arnold DM, Dentali F, Crowther MA, Meyer RM, Cook RJ, Sigouin C, Fraser GA, Lim W, Kelton JG.
    Systematic Review: Efficacy and Safety of Rituximab for Adults with Idiopathic Thrombocytopenic Purpura.
    Ann Intern Med 2007;146:25-33. PMID: 17200219

  • Arnold DM, Nazi I, Santos A, Chan H, Heddle NM, Warkentin TE, Kelton JG.
    Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood 2010;115:29-31. PMID:19897578

  • Aster RH.
    Can drugs cause autoimmune thrombocytopenic purpura?
    Semin Hematol 2000;37:229-238. PMID:10942217

  • Aster RH, Bougie DW.
    Current concepts: drug-induced immune thrombocytopenia.
    N Engl J Med 2007;357:580-587. PMID: 17687133

  • Aster RH, Curtis BR, McFarland JG, Bougie DW.
    Drug-induced immune thrombocytopenia: pathogenesis, diagnosis, and management.
    J Thromb Haemost 2009;7:911-918. PMID: 19344362

  • Bae SH. Ryoo HM, Lee WS, Joo YD, Lee KH, Lee JH, Lee JH, Kim H, Park JH, Kim MK, Hyun M, Kim HJ, Zang DY.
    High Dose Dexamethasone Vs. Conventional Dose Prednisolone for Adults with Immune Thrombocytopenia: a Prospective Multicenter Phase III Trial.
    Blood 2010;116(Suppl.):1512, Abstr. #3687

  • Bain BJ.
    Bone marrow biopsy morbidity and mortality.
    Br J Haematol 2003;121:949-951. PMID:12786808

  • Bain BJ.
    Bone marrow biopsy morbidity and mortality: 2002 data.
    Clin Lab Haematol 2004;26:315-318. PMID:15485459

  • Bain BJ.
    Morbidity associated with bone marrow aspiration and trephine biopsy — a review of UK data for 2004.
    Haematologica 2006;91:1293-1294. PMID:16956842

  • Balfour HH Jr.
    Antiviral drugs.
    N Engl J Med 1999;340:1255-1268. PMID:10210711

  • Ballem PJ, Segal GM, Stratton J, Gernsheimer T, Adamson JW, Slichter SJ.
    Mechanism of thrombocytopenia in chronic autoimmune thormbocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.
    J Clin Invest 1987;80:33-40. PMID:3597777

  • Barnes C, Blanchette V, Canning P, Carcao M.
    Recombinant FVIIa in the management of intracerebral haemorrhage in severe thrombocytopenia unresponsive to platelet-enhancing treatment.
    Transfus Med 2005;15:145-150. PMID:15859982

  • Barrett JC, Call SA, Arndt DW, Dudley KA, Mahan JA, Saleh MN.
    Thrombocytopenia with platelet-associated IgM antibodies: patient characteristics and responsiveness to ITP therapy.
    Blood 1998;92(Suppl.1):82b.

  • Barrett YC, Ebling W, Pieniaszek H, Billheimer J, Seiffert D.
    Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist.
    J Pharm Biomed Anal 2007;44:938-946. PMID:17485191

  • Basser RL, O’Flaherty E, Green M, Edmonds M, Nichol J, Menchaca DM, Cohen B, Begley CG.
    Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor.
    Blood 2002;99:2599-2602. PMID:11895799

  • Baumann MA, Menitove JE, Aster RH, Anderson T.
    Urgent treatment of idiopathic thrombocytopenic purpura with single-dose gammaglobulin infusion followed by platelet transfusion.
    Ann Intern Med 1986;104:808-809. PMID:2422997

  • Bednar B, Cook JJ, Holahan MA, Cunningham ME, Jumes PA, Bednar RA, Hartman GD, Gould RJ.
    Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa.
    Blood 1999;94:587-599. PMID:10397726

  • Bell WR.
    Long-term outcome of splenectomy for idiopathic thrombocytopenic purpura.
    Semin Hematol 2000;37(suppl. 1):22-25. PMID:10676920

  • Bellucci S, Charpak V, Chastang C, Tobelem G.
    Low Doses vs Conventional Doses of Corticoids in Immune Thrombocytopenic Purpura (ITP): Results of a Randomized Clinical Trial in 160 Children, 223 Adults.
    Blood 1988;71:1165-1169.

  • Ben-Yehuda D, Gillis S, Eldor A and the Israeli ITP Study Group.
    Clinical and therapeutic experience in 712 Israeli patients with idiopathic thrombocytopenic purpura.
    Acta Haematol 1994;91:1-6. PMID:8171929

  • Berkman N, Michaeli Y, Or R, Eldor A.
    EDTA-dependent pseudothrombocytopenia: a clinical study of 18 patients and a review of the literature.
    Am J Hematol 1991;36:195-201. PMID:1899964

  • Berkowitz SD, Harrington RA, Rund MM, Tcheng JE.
    Acute profound thrombocytopenia after c7E3 (abciximab) therapy.
    Circulation 1997;95:809-813. PMID:9054735

  • Bettaieb A, Oksenhendler E, Duedari N, Bierling P.
    Cross-reactive antibodies between HIV-gp120 and platelet GP IIIa (CD61) in HIV-related imune thrombocytopenic purpura.
    Clin Exp Immunol 1996;103:19-23. PMID:8565280

  • Billheimer JT, Dicker IB, Wynn R, Bradley JD, Cromley DA, Godonis HE, Grimminger LC, He B, Kieras CJ, Pedicord DL, Spitz SM, Thomas BE, Zolotarjova NI, Gorko MA, Hollis GF, Daly RN, Stern AM, Seiffert D.
    Evidence that thrombocytopenia observed in humans treated with orally bioavailable glycoprotein IIb/IIIa antagonists is immune mediated.
    Blood 2002;99:3540-3546. PMID:11986205

  • Blanchette M, Freedman J.
    The History of Idiopathic Thrombocytopenic Purpura (ITP)
    Transfus Sci Vol 1998;19:231-236. PMID:10351134

  • Boccia R, Kuter DJ, Rummel MJ, Macik BG, Pabinger I, Selleslag D, Rodeghiero F, Chong B, Wang X, Lizambri R.
    The Effects of Romiplostim or Standard of Care (SOC) on Splenectomy and Treatment Failure of Patients Who Had Immune Thrombocytopenia (ITP) for Less Than or Equal to One Year.
    Blood 2010;116 (Suppl):1519, Abstr. #3702.

  • Bolton-Mages PHB, Moon I.
    Assessment of UK practice for management of acute childhood idiopathic thrombocytopenic purpura (ITP) against published guidelines.
    Lancet 1997;350:620-623. PMID:9288044

  • Bolton-Maggs PHB, Moon I.
    National audit of the management of childhood idiopathic thrombocytopenic purpura against UK guidelines: closing the loop - education and re-audit demonstrate a change in practice.
    Blood 2001;98(Suppl1,Part2):58b, Abstr. #3847.

  • Bonderman D, Jakowitsch J, Adlbrecht C, Schemper M, Kyrle PA, Schönauer V, Exner M, Klepetko W, Kneussl MP, Maurer G, Lang I.
    Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension.
    J Thromb Haemost 2005;93:512-516. PMID:15735803

  • Borst F, Keuning JJ, van Hulsteijn H, Sinnige H, Vreugdenhil G.
    High-dose dexamethasone as a first- and second-line treatment of idiopathic thrombocytopenic purpura in adults.
    Ann Hematol 2004;83:764-768. PMID:15309522

  • Boruchov DM, Gururangan S, Driscoll MC, Bussel JB.
    Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP).
    Blood 2007;110:3526-3531. PMID:17698634

  • Bouldouyre MA, Charreau I, Marchou B, Tangre P, Katlama C, Morlat P, Meiffredy V, Vittecoq D, Bierling P, Aboulker JP, Molina JM; ANRS 106 Study Group.
    Incidence and risk factors of thrombocytopenia in patients receiving intermittent antiretroviral therapy: a substudy of the ANRS 106-window trial.
    J Acquir Immune Defic Syndr 2009;52:531-537. PMID:19855285

  • British Committee for Standards in Haematology, Blood Transfusion Task Force.
    Guidelines for the use of platelet transfusions.
    Br J Haematol 2003a;122:10-23. PMID:12823341

  • British Committee for Standards in Haematology General Haematology Task Force.
    Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy.
    Br J Haematol 2003b;120:574-96. PMID:12588344

  • Buchanan GR, Adix L.
    Grading of hemorrhage in children with idiopathic thrombocyto¬penic purpura.
    J Pediatr 2002;141:683-688. PMID:12410198

  • Budde U, Schmidt R, Gerloff J, Etzel F.
    Therapie einer refraktären Idiopathischen Thrombozytopenischen Purpura mit Vinblastin-beladenen Thrombozyten.
    Blut 1979;38:139-141. PMID:570071

  • Bundesärztekammer.
    Querschnitts-Leitlinien (BÄK) zur Therapie mit Blutkomponenten und Plasmaderivaten. 4. überarbeitete Auflage.
    Deutscher Ärzteverlag 2009.
    Die Leitlinien sind abrufbar unter www.baek.de/haemotherapie

  • Burrows RF, Kelton JG.
    Fetal thrombocytopenia and its relation to maternal thormbocytopenia.
    N Engl J Med 1993a;329:1463-1466. PMID:8413457

  • Burrows RF, Kelton JG.
    Pregnancy in patients with idiopathic thrombocytopenic purpura: assessing the risks for the infant at delivery.
    Obstet Gynecol Surv 1993b;48:781-788. PMID:8309660

  • Bussel JB.
    Immune thrombocytopenia in pregnancy: autoimmune and alloimmune.
    J Reprod Immunol 1997;37:35-61. PMID:9501289

  • Bussel JB.
    Management of children with ITP at diagnosis: consensus and controversy.
    Blood 1999;94(Suppl1):78b.

  • Bussel JB, Cheng G, Saleh MN, Mayer B, Vasey SY, Brainsky A.
    Incidence of Thromboembolic Events Across Eltrombopag Clinical Trials In Chronic Immune Thrombocytopenia (ITP).
    Blood 2010;116(Suppl):37, Abstr. #70.

  • Bussel JB, Cheng G, Saleh MN, Psaila B, Kovaleva L, Meddeb B, Kloczko J, Hassani H, Mayer B, Stone NL, Arning M, Provan D, Jenkins JM.
    Eltrombopag for the treatment of chronic idiopathic thrombocytpenic purpura.
    N Engl J Med 2007;357:2237-2247. PMID:18046028

  • Bussel JB, Graziano JN, Kimberly RP, Pahwa S, Aledort LM.
    Intravenous anti-D treatment of immune thrombocytopenic purpura: analysis of efficacy, toxicity, and mechanism of effect.
    Blood 1991;77:1884-1893. PMID:1850307

  • Bussel J, Kaplan C.
    The fetal and neonatal consequences of maternal alloimmune thrombocytopenia.
    Baillière's Clinical Haematology 1998;11:391-408. PMID:10097816

  • Bussel JB, Kuter DJ, George JN, McMillan R, Aledort LM, Conklin GT, Lichtin AE, Lyons RM, Nieva J, Wasser JS, Wiznitzer I, Kelly R, Chen C, Nichol JL.
    AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP.
    N Engl J Med 2006;355:1672-1681. PMID:17050891

  • Bussel JB, Kuter DJ, Pullarkat V, Lyons RM, Guo M, Nichol JL.
    Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP.
    Blood 2009a;113:2161-2171. PMID:18981291

  • Bussel JB, Pham LC.
    Intravenous treatment with gammaglobulin in adults with immune thrombocytopenic purpura: review of the literature.
    Vox Sang 1987;52:206-210. PMID:2440183

  • Bussel JB, Provan D, Shamsi T, Cheng G, Psaila B, Kovaleva L, Salama A, Jenkins JM, Roychowdhury D, Mayer B, Stone N, Arning M.
    Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial.
    Lancet 2009b;373:641-648. PMID:19231632

  • Calverley DC, Jones GW, Kelton JG.
    Splenic radiation for corticosteroid-resistant immune thrombocytopenia.
    Ann Intern Med 1992;116:977-981. PMID:1586107

  • Caress JB, Hobson-Webb L, Passmore LV, Finkbiner AP, Cartwright MS.
    Case-control study of thromboembolic events associated with IV immunoglobulin.
    J Neurol 2009;256:339-342. PMID:19253011

  • Carr JM, Kruskall MS, Kaye JA, Robinson SH.
    Efficacy of platelet transfusions in immune thrombocytopenia.
    Am J Med 1986;80:1051-1054. PMID:3728504

  • Cavalli F.
    Rare syndromes in Hodgkin's disease.
    Ann Oncol 1998;9 (Suppl5):S109-S113. PMID:9926248

  • Cavenagh JD, Macey MG, Newell MS, Garvey N, Newland AC.
    Predicting the outcome of splenectomy in C patients utilising 111In-labelled platelet studies.
    British Journal of Haematology 1999;105:48

  • Carson KR, Evens AM, Richey EA, Habermann TM, Focosi D, Seymour JF, Laubach J, Bawn SD, Gordon LI, Winter JN, Furman RR, Vose JM, Zelenetz AD, Mamtani R, Raisch DW, Dorshimer GW, Rosen ST, Muro K, Gottardi-Littell NR, Talley RL, Sartor O, Green D, Major EO, Bennett CL.
    Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.
    Blood 2009;113:4834-4840. PMID:19264918

  • Chang M, Nakagawa PA, Williams SA, Schwartz MR, Imfeld KL, Buzby JS, Nugent DJ.
    Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vi¬tro.
    Blood. 2003;102:887-895. PMID:12676790

  • Cheng Y, Wong RS, Soo YO, Chui CH, Lau FY, Chan NP, Wong WS, Cheng G.
    Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone.
    N Engl J Med 2003;349:831-836. PMID:12944568

  • Choufi B, Tournilhac O, Cure H, Brahimi S, Eychenne D, By J, Fleury J, plagne R, Travade P
    Immune thrombocytopenic purpura in Hodgkin's disease.
    Blood 1999;94(Suppl1):244b.

  • Christiaens GCML.
    Immune thrombocytopenic purpura in pregnancy.
    Baillière's Clinical Haematology 1998;11:373-380. PMID:10097814

  • Cines DB, Blanchette VS.
    Immune thrombocytopenic purpura.
    N Engl J Med 2002;346:995-1008. PMID:11919310

  • Cohen YC, Djulbegovic B, Shamai-Lubovitz O, Mozes B.
    The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet¬counts.
    Arch Intern Med 2000;160:1630-1638. PMID:10847256

  • Cooper N, Evangelista ML, Amadori S, Stasi R.
    Should rituximab be used before or after splenectomy in patients with immune thrombocytopenic purpura.
    Curr Opin Hematol 2007;14:642-646. PMID:17898569

  • Crary SE, Buchanan GR.
    Vascular complications after splenectomy for hematologic disorders.
    Blood 2009;114:2861-2868. PMID:19636061

  • Cuker A, Cines DB.
    Evidence-based mini-review: is indium-labeled autologous platelet scanning predictive of response to splenectomy in patients with hronic immune thrombocytopenia?
    Hematology Am Soc Hematol Educ Program 2010;2010:385-386. PMID:21239823

  • Curtis BR, Swyers J, Divgi A, McFarland JG, Aster RH.
    Thrombocytopenia after second exposure to abciximab is caused by antibodies that recognize abciximab-coated platelets.
    Blood 2002;99:2054-2059. PMID:11877279

  • Dabak V, Hanbal Ai, Kuriakose P.
    Can Rituximab Replace Splenectomy in Immune Thrombocytopenic Purpura (ITP)?
    Blood 2007;110 (Suppl. 1, Part 1):393a, Abstr. #1306.

  • Dameshek W, Miller EB.
    The megakaryocytes in idiopathic thrombocytopenic purpura. A form of hypersplenism.
    Blood 1946;1:27-51. PMID:21013546

  • Davies JM, Barnes R, Milligan D.
    Update of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen
    Clin Med 2002;2:440-443. PMID:12448592

  • de Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang WJ, et al.
    Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.
    Nature 1994;369:533-538. PMID:8202154

  • Dickerhoff R, Gaedicke G, Sutor H.
    Leitlinie K4a: Akute Immun-Thrombozytopenie (ITP).
    In: Deutsche Gesellschaft für Kinderheilkunde und Jugendmedizin: Leitlinien Kinderheilkunde und Jugendmedizin.
    Urban und Fischer Verlag, 2006

  • DiFino SM, Lachant NA, Kirshner JJ, Gottlieb AJ.
    Adult idiopathic thrombocytopenic purpura. Clinical findings and response to therapy.
    Am J Med 1980;69:430-442. PMID:6998293

  • Djulbegovic B, Cohen Y.
    The natural history of refractory idiopathic thrombocytopenic purpura.
    Blood 2001;98:2282-2283. PMID:11592263

  • Doan CA, Bouroncle BA, Wiseman BK.
    Idiopathic and secondary thrombocytopenic purpura: clinical study and evaluation of 381 cases over a period of 28 years.
    Ann Intern Med 1960;53:861-876.

  • Dong F, Li S, Pujol-Moix N, Luban NL, Shin SW, Seo JH, Ruiz-Saez A, Demeter J, Langdon S, Kelley MJ.
    Genotype-phenotype correlation in MYH9-related thrombocytopenia.
    Br J Haematol 2005;130:620-627. PMID:16098078

  • El-Najjar I, Rule SAJ, Nokes TCJ.
    A fixed, low dose of anti-CD20 antibody (Rituximab) is an effective treatment for patients with chronic immune thrombocytopenia.
    Br J Haematol 2006;133(Suppl1):79, Abstr. #196

  • Emilia G, Longo G, Luppi M, Gandini G, Morselli M, Ferrara L, Amarri S, Cagossi K, Torelli G.
    Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura.
    Blood 2001;97:812-814. PMID:11157503

  • Emmons RBV, Reid DM Cohen RL, Meng G, Young NS, Dunbar CE, Shulman NR.
    Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.
    Blood 1996;87:4068-4071. PMID:8639762

  • Epstein CJ, Sahud MA, Piel CF, Goodman JR, Bernfield MR, Kushner JH, Albin AR.
    Hereditary macrothrombocytopathia, nephritis and deafness.
    Am J Med 1972;52:299-310. PMID:5011389

  • Facon T, Caulier MT, Fenaux P, Plantier I, Marchandise X, Ribet M, Jouet JP, Bauters F.
    Accessory spleen in recurrent chronic immune thrombocytopenic purpura.
    Am J Hematol 1992;41:184-189. PMID:1415193

  • Fanucchi M, Glaspy J, Crawford J, Garst J, Figlin R, Sheridan W, Menchaca D, Tomita D, Ozer H, Harker L.
    Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer.
    N Engl J Med 1997;336:404-409. PMID:9010146

  • Fenaux P, Caulier MT, Hirschauer C, Beuscart R, Goudemand J, Bauters F.
    Reevaluation of the prognositc factors for splenectomy in chronic idiopathic thrombocytopenic purura.
    Eur J Haematol 1989;42:259-264. PMID:2924888

  • Feudjo-Tepie MA, Hall SA, Logie JW, Bennett D.
    The Incidence of Idiopathic Thrombo-cytopenic Purpura (ITP) among Adults in the United Kingdom s General Practice Research Database (GPRD), 1992-2005.
    Blood 2007;110(Suppl1,Part1):942a Abstr. #3209

  • Feudjo-Tepie MA, Robinson NJ, Bennett D.
    Prevalence Estimates of Adult Chronic Idio¬pathic Thrombocytopenic Purpura (ITP) in the United States.
    J Thromb Haemost 2008;6:711-712. PMID:18221355

  • Figueroa M, Gehlsen J, Hammond D, Ondreyco S, Piro L, Pomeroy T, Williams F, McMillan R.
    Combination chemotherapy in refractory immune thrombocytopenic purpura.
    N Engl J Med 1993;328:1226-1229. PMID:8464433

  • Fogarty PF, Bussel JB, Cheng G, et al.
    Oral eltrombopag treatment reduces the need for concomitant medications in patients with chronic idiopathic thrombocytopenic purpura.
    Blood 2008;112:1174. Abstr. #3424

  • Foster CB, Zhu S, Erichsen HC, Lehrnbecher T, Hart ES, Choi E, Stein S, Smith MW, Steinberg SM, Imbach P, Kühne T, Chanock SJ; Early Chronic ITP Study Group.
    Polymorphisms in inflammatory cytokines and Fcgamma receptors in childhood chronic immune thrombocytopenic purpura: a pilot study.
    Br J Haematol 2001;113:596-599. PMID:11380443

  • Frederiksen H, Schmidt K.
    The incidence of idiopathic thrombocytopenic purpura in adults increases with age.
    Blood 1999;94:909-913. PMID:10419881

  • Gaines AR.
    Disseminated intravascular coagulation associated with acute hemoglobinemia or hemoglobinuria following Rh0(D) immune globulin intravenous administration for immune thromboctopenic purpura.
    Blood 2005;106:1532-1537. PMID:15878975

  • Gasbarrini A, Franceschi F, Tartaglione R, Landolfi R, Pola P, Gasbarrini G.
    Regression of auto-immune thrombocytopenia after eradication of Helicobacter pylori.
    Lancet 1998;352:878. PMID: 9742983

  • Gaydos LA, Freireich EJ, Mantel N.
    The quantitative relation between platelet count and hemorrhage in patients with acute leukemia.
    N Engl J Med 1962;266:905-909. PMID:13897369

  • George J.
    Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the orign of alpha-granule proteins.
    Blood 1990;76:859-870. PMID:2203482

  • George JN, Berkowitz SD, Raksob GE.
    Platelets: acute thrombocytopenia.
    Am Soc Hematol Educ Program Book 1998a:371-383.

  • George JN, El-Harake MA, Raskob GE.
    Chronic Idiopathic Thrombocytopenic Purpura.
    N Engl J Med 1994;331:1207-1211. PMID:7935660

  • George JN, Mathias SD, Go RS, Guo M, Henry DH, Lyons R, Redner RL, Rice L, Schipperus MR.
    Improved quality of life for romiplostim-treated patients with chronic immune thrombocytopenic purpura: results from two randomized, placebo-controlled trials.
    Br J Haematol 2009;144:409-415. PMID:19016720

  • George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, Lichtin AE, McMillan R, Okerbloom JA, Regan DH, Warrier I.
    Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology.
    Blood 1996;88:3-40. PMID:8704187

  • Gernsheimer TB, George JN, Aledort LM, Tarantino MD, Sunkara U, Matthew Guo D, Nichol JL.
    Evaluation of bleeding and thrombotic events during long-term use of romiplostim in patients with chronic immune thrombocytopenia (ITP).
    J Thromb Haemost 2010;8:1372-1382. PMID:20230419

  • Gill KK, Kelton JG.
    Management of idiopathic thrombocytopenic purpura in pregnancy.
    Semin Hematol 2000;37:275-289. PMID:10942222

  • Gillis S, Eldor A.
    Immune thrombocytopneic purpura in adults: clinical aspects.
    Baillière's Clinical Hematology 1998;11:361-372. PMID:10097813

  • Godeau B, Caulier MT, Decuypere L, Bierling P.
    Intravenous immunoglobulin for adults with autoimmune thrombocytopenic purpura: results of a randomized trial comparing 0.5 and 1g/kg body weight.
    Br J Haematol 1999;107:716-719. PMID:10606875

  • Godeau B, Chevret S, Varet B, Lefrere F, Zini JM, Bassompierre F, Cheze S, Legouffe E, Hulin C, Grange MJ, Fain O, Bierling P.
    Intravenous immunoglobulin or high-dose methylprednisolone, with or without oral prednisone, for adults with untreated severe autoimmune thrombocytopenic purpura: a randomised, multicentre trial.
    Lancet 2002;359:23-29. PMID:11809183

  • Godeau B, Porcher R, Fain O, Lefrère F, Fenaux P, Cheze S, Vekhoff A, Chauveheid MP, Stirnemann J, Galicier L, Bourgeois E, Haiat S, Varet B, Leporrier M, Papo T, Khellaf M, Michel M, Bierling P.
    Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura - results of a prospective multicenter phase 2 study.
    Blood 2008;112:999-1004. PMID:18463354

  • Gómez-Almaguer D, Solano-Genesta M, Tarín-Arzaga L, Herrera-Garza JL, Cantú-Rodríguez OG, Gutiérrez-Aguirre CH, Jaime-Pérez JC.
    Low-dose rituximab and alemtuzumab combination therapy for patients with steroid-refractory autoimmune cytopenias.
    Blood 2010;116:4783-4785. PMID:20841509

  • Greinacher A.
    Seltene hereditäre Thrombozytopenien und Thrombozytopathien.
    In: Müller-Berghaus G, Pötzsch B (Hrsg).
    Springer Verlag, 1998;72-82.

  • Greinacher A, Kiefel V, Klüter H, Kroll H, Pötzsch B, Riess H.
    Empfehlungen zur Thrombozytentransfusion - Thrombozyten Arbeitsgruppe der DGTI, GTH und DGHO.
    Dtsch Med Wochenschr 2006;131:2675-2679. PMID:17109279

  • Greinacher A, Nieuwenhuis HK, White JG.
    Sebastian platelet syndrome: a new variant of hereditary macrothrombocytopenia with leukocyte inclusions.
    Blut 1990;61:282-288. PMID:2176899

  • Greinacher A, Selleng K.
    Thrombocytopenia in the Intensive Care Unit Patient.
    Hematology Am Soc Hematol Educ Program 2010:135-143. PMID:21239783

  • Gunay-Aygun M, Zivony-Elboum Y, Gumruk F, Geiger D, Cetin M, Khayat M, Kleta R, Kfir N, Anikster Y, Chezar J, Arcos-Burgos M, Shalata A, Stanescu H, Manaster J, Arat M, Edwards H, Freiberg AS, Hart PS, Riney LC, Patzel K, Tanpaiboon P, Markello T, Huizing M, Maric I, Horne M, Kehrel BE, Jurk K, Hansen NF, Cherukuri PF, Jones M, Cruz P, Mullikin JC, Nurden A, White JG, Gahl WA, Falik-Zaccai T.
    Gray platelet syndrome: natural history of a large patient cohort and locus assignment to chromosome 3p.
    Blood 2010;116:4990-5001. PMID:20709904

  • Gustin D, Warren T, Buntinas R.
    Idiopathic thrombocytopenic purpura the utility of the bone marrow examination in adults.
    Blood 1998;92(Suppl1):176a.

  • Handin RI.
    Inherited platelet disorders.
    Hematology Am Soc Hematol Educ Program 2005:396-402. PMID:16304410

  • Harrington WJ, Minnich V, Hollingsworth JW, Moore CV.
    Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura.
    J Lab Clin Med 1951;38:1-10. PMID:2187937

  • Heddle NM, Cook RJ, Tinmouth A, Kouroukis CT, Hervig T, Klapper E, Brandwein JM, Szczepiorkowski ZM, AuBuchon JP, Barty RL, Lee KA; SToP Study Investigators of the BEST Collaborative.
    A Randomized Controlled Trial Comparing Standard and Lowdose Strategies for Transfusion of Platelets (SToP) to Patients With Thrombocytopenia.
    Blood 2009;113:1564-1573. PMID:19109560

  • Heyns AD, Lotter MG, Badenhorst PN, de Kock F, Pieters H, Herbst C, van Reenen OR, Kotze H, Minnaar PC.
    Kinetics and sites of destruction of 111-Indium-oxine-labeled platelets in idiopathic thormbocytopenic purpura: a quantitative study.
    Am J Hematol 1982;12:167-177. PMID:7200322

  • Hoeper MM, Niedermeyer J, Hoffmeyer F, Flemming P, Fabel H.
    Pulmonary hypertension after splenectomy?
    Ann Internal Med 1999;130:506-509.

  • Houwerzijl EJ, Blom NR, van der Want JJL, Louwes H, Esselink MT, Smit JW, Vellenga E, de Wolf JT.
    Ultrastructural study shows morphol¬ogic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura.
    Blood 2004;103:500-506. PMID:12969975

  • Huhn RD, Fogarty PF, Nakamura R, Read EJ, Leitman SF, Rick ME, Kimball J, Greene A, Hansmann K, Gratwohl A, Young N, Barrett AJ, Dunbar CE.
    High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia.
    Blood 2003;101:71-77. PMID:12393623

  • Hurtado RM, Myrna CH, Silmia CM, Juan SM, Juan OC, Manuel BR, Carolina GG, Pablo VV, Miguel PJ, Arturo L, Martha K.
    Autologous stem cell transplantation for autoimmune disorders a case report.
    Blood 1999;94(Suppl1):401b.

  • Ikeda Y, Miyakawa Y.
    Development of thrombopoietin receptor agonists for clinical use.
    J Thromb Haemost 2009;7(Suppl1):239-244. PMID:19630808

  • Jaglowski SM, Byrd JC, Jones JA.
    In-Hospital Mortality and Trends Associated with Splenectomy in Patients with Immune-Mediated Thrombocytopenia (ITP).
    Blood 2009;114:569 Abstr. #1398.

  • Jaïs X, Ioos V, Jardim C, Sitbon O, Parent F, Hamid A, Fadel E, Dartevelle P, Simonneau G, Humbert M.
    Splenectomy and chronic thromboembolic pulmonary hypertension.
    Thorax 2005;60:1031-1034. PMID:16085731

  • Jantunen E.
    Inherited giant platelet disorders.
    Eur J Haematol 1994;53:191-196. PMID:7957801

  • Jara Sánchez C, Olier Gárate C, García-Donas Jiménez J, Peñalver Párraga J.
    Drug-induced thrombocytopenia induced by trastuzumab: a special challenge in a curable disease.
    Ann Oncol 2009;20:1607-1608. PMID:19633054

  • Jawa V, Hokom M, Hu Z, El-Abaadi N, Zhuang Y, Berger D, Gupta S, Swanson S, Chirmule N.
    Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects.
    Ann Hematol 2010;89(Suppl1):75-85.

  • Johnston PB, Inwards DJ.
    Rituximab-associated immune thrombocytopenic purpura.
    Blood 1999;94(Suppl.1):263b.

  • Jubelirer SJ, Harpold R.
    The role of the bone marrow examination in the diagnosis of immune thrombocytopenic purpura: case series and literature review.
    Clin Appl Thromb Hemost 2002;8:73-76. PMID:11991243

  • Juliá A, Araguás C, Rosselló J, Bueno J, Domenech P, Olona M, Guardia R, Petit J, Flores A.
    Lack of useful clinical predictors of response to splenectomy in patients with chronic idiopathic thrombocytopenic purpura.
    Br J Haematol 1990;76:250-255. PMID:2094326

  • Kaplan C, Daffos F, Forestier F, Tertian G, Catherine N, Pons JC, Tchernia G.
    Fetal platelet counts in thrombocytopenic pregnancy.
    Lancet 1990;336:979-982. PMID:1977013

  • Karpatkin S, Charmatz A.
    Heterogeneity of human platelets. I. Metabolic and kinetic evidence suggestive of young and old platelet.
    J Clin Invest 1969;48:1073-1082. PMID:5771188

  • Kattamis J, Shankar S, Cohen AR.
    Neurologic complications of treatment of childhood acute immune thrombocytopenic purpura with intravenously administered immunoglobulin.
    J Pediatr 1997;130:281-283. PMID:9042132

  • Kaznelson P.
    Verschwinden der hämorrhagischen Diathese bei einem Falle von "essentieller Thrombopenie" (Frank) nach Milzextirpation: Splenogene thrombolytische Purpura.
    Wien Klien Wochenschr 1916;29:1451-1454.

  • Keeling D, Davidson S, Watson H on behalf of the Maeostasis and Thrombosis Task Force of the British Committee for Standards in Haematology.
    The management of heparin-induced thrombocytopenia.
    Br J Haematol 2006;133:259-269. PMID:16643427

  • Kelton JG.
    Vaccination-Associated relapse of immune thrombocytopenia.
    JAMA 1981;245:369-370. PMID:6969806

  • Kelton JG, McDonald JWD, Barr RM, Walker I, Nicholson W, Neame PB, Hamid C, Wong TY, Hirsh J.
    The reversible binding of vinblastine to platelets: implications for therapy.
    Blood 1981;57:431-438. PMID:7459430

  • Khellaf M, Michel M, Bierling P, Godeau B.
    Assessment of a therapeutic strategy for adults with severe autoimmune thrombocytopenic purpura based on a bleeding score rather than platelet count.
    Haematologica 2005;90:829-832. PMID:15951296

  • Kiefel V, Bassler D, Kroll H, Paes B, Giers G, Ditomasso J, Alber H, Berns M, Wiebe B, Quenzel EM, Hoch J, Greinacher A.
    Antigen-positive platelet transfusion in neonatal alloimmune thrombocytopenia (NAIT).
    Blood 2006;107:3761-3763. PMID:16403916

  • Kiefel V, Santoso S, Weisheit M.
    Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet reactive antibodies.
    Blood 1987;70:1722-1726. PMID:2445398

  • Kohda K, Kuga T, Kogawa K, Kanisawa Y, Koike K, Kuroiwa G, Hirayama Y, Sato Y, Niitsu Y.
    Effect of helicobacter pylori eradication on platelet recovery in Japanese patients wtih chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura.
    Br J Haematol 2002;118:584-588. PMID:12139750

  • Koike Y, Yoneyama A, Shirai J, Ishida T, Shoda E, Miyazaki K, Sunaga S, Horie R, Aoki K, Koike K, Ogata I, Tahara T, Kato T, Nakahara K, Kariya T, Higashihara M.
    Evaluation of thrombopoiesis in thrombocytopenic disorders by simultaneous measurement of reticulated platelets of whole blood and serum thrombopoietin concentrations.
    Thromb Haemost 1998;79:1106-1110. PMID:9657432

  • Kojouri K, Vesely SK, Terrell DR, George JN.
    Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses , prediction of response, and surgical complications.
    Blood 2004;104:2623-2634. PMID:15217831

  • Kroll H, Yates J, Santoso S.
    Immunization against a low-frequency human platelet alloantigen in fetal alloimmune thrombocytopenia is not a single event: characterization by the combined use of reference DNA and novel allele-specific cell lines expressing recombinant antigens.
    Transfusion 2005;45:353-358. PMID:15752152

  • Kühne T, Imbach P, Bolton-Maggs PHB, Berchtold W, Blanchette V, Buchanan GR for the Intercontinental Childhood ITP Study Group.
    Newly diagnosed idiopathic thrombocytopenic purpura in childhood: an observational study.
    Lancet 2002;358:2122-2125. PMID:11784627

  • Kuter DJ.
    New thrombopoietic growth factors.
    Blood 2007;109:4607-4616. PMID:17289815

  • Kuter DJ, Bussel JB, Newland A, Wasser JS, Lyons RM, George JN, Macik G, Nie K, Jun S.
    Long-Term Efficacy and Safety of Romiplostim Treatment of Adult Patients with Chronic Immune Thrombocytopenia (ITP): Final Report from an Open-Label Extension Study.
    Blood 2010a;116(Suppl):36 Abstr. #68.

  • Kuter DJ, Bussel JB, Lyons RM, Pullarkat V, Gernsheimer TB, Senecal FM, Aledort LM, George JN, Kessler CM, Sanz MA, Liebman HA, Slovick FT, de Wolf JT, Bourgeois E, Guthrie TH Jr, Newland A, Wasser JS, Hamburg SI, Grande C, Lefrère F, Lichtin AE, Tarantino MD, Terebelo HR, Viallard JF, Cuevas FJ, Go RS, Henry DH, Redner RL, Rice L, Schipperus MR, Guo DM, Nichol JL.
    Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial.
    Lancet 2008;371:395-403. PMID:18242413

  • Kuter DJ, Mufti GJ, Bain BJ, Hasserjian RP, Davis W, Rutstein M.
    Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim.
    Blood 2009;114:3748-3756. PMID:19671919

  • Kuter DJ, Rummel M, Boccia R, Macik BG, Pabinger I, Selleslag D, Rodeghiero F, Chong BH, Wang X, Berger DP.
    Romiplostim or standard of care in patients wtih immune thrombocytopenia.
    N Engl J Med 2010b;363:1889-1999. PMID:21067381

  • Kuwana M, Okazaki Y, Ikeda Y.
    Splenic macrophages maintain the anti-platelet autoimmune response via uptake of opsonized platelets in patients with immune thrombocytopenic purpura.
    J Thromb Haemost 2009;7:322-329. PMID:18826388

  • Lacey JV, Penner JA.
    Management of idiopathic thrombocytopenic purpura in the adult.
    Semin Thromb Hemost 1977;3:160-174. PMID:322290

  • Lalazar G, Rund D, Shouval D.
    Screening, prevention and treatment of viral hepatitis B reactivation in patients with haematological malignancies.
    Br J Haematol 2007;136:699-712. PMID:17338776

  • Law C, Marcaccio M, Tam P, Heddle N, Kelton JG.
    High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura.
    N Engl J Med 1997;336:1494-1498. PMID:9154768

  • Levi M, Levy JH, Andersen HF, Truloff D.
    Safety of Recombinant Activated Factor VII in Randomized Clinical Trials
    N Engl J Med 2010; 363:1791-1800. PMID:21047223

  • Li J, Yang C, Xia Y, Bertino A, Glaspy J, Roberts M, Kuter DJ.
    Thrombocytopenia caused by the development of antibodies to thrombopoietin.
    Blood 2001;98:3241-3248. PMID:11719360

  • Li X, Zhong J, Bao W, Boulad N, Bussel JB, Yazdanbakhsh K.
    Regulatory B Cell Defects In Patients with Immune Thrombocytopenia (ITP).
    Blood 2010;116(Suppl):171, Abstr. #379.

  • Liebman HA, Henry D, Lefrere F.
    Long-term safety profile of romiplostim in patients with chronic immune thrombocytopenia (ITP).
    Blood 2008;112 (Suppl1):1171, Abstr. #3415.

  • Lim SH, Hale G, Marcus RE, Waldmann H, Baglin TP.
    CAMPATH-1 monoclonal antibody therapy in severe refractory autoimmune thrombocytopenic purpura.
    Br J Haematol 1993;84:542-544. PMID:8217808

  • Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, et al.
    Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo.
    Nature 1994;369:565-568. PMID:8202158

  • Lortan JE.
    Management of asplenic patients.
    Br J Haematol 1993;84:566-569. PMID:8217814

  • Louwes H, Zeinali Lathori OA, Vellenga E, de Wolf JT.
    Platelet kinetic studies in pa¬tients with idiopathic thrombocytopenic purpura.
    Am J Med 1999;106:430-434. PMID:10225246

  • Lozano ML, Curtis BR, Hansen RM, Bayliss K, Petersen JA, Aster RH.
    A GP IIb/IIIa-specific autoantibody from a patient with acquired amegakaryocytic thrombocytopenia appears to be the first example of a human ligand mimetic immunoglobulin.
    Blood 1998;92(Suppl1):175a.

  • Mahabir VK, Ross C, Popovic S, Bourgeois J, Wang G, George JN, Lim W, Kelton JG, Arnold DM.
    The Utility of Bone Marrow Examinations for the Diagnosis of Immune Thrombocytopenia.
    Blood 2010;116(Suppl.):1514, Abstr. #3691.

  • Mahler M, Hasan A, Bussel JB.
    Rituximab Maintenance Treatment In Immune Mediated Thrombocytopenia (ITP) Including Evans Syndrome.
    Blood 2010;116(Suppl):1046, Abstr. #2523.

  • Malempati S, Joshi S, Lai S, Braner DA, Tegtmeyer K.
    Videos in clinical medicine. Bone marrow aspiration and biopsy.
    N Engl J Med 2009;361:e28. PMID:19812396

  • Mannucci PM.
    Hemostatic Drugs.
    N Engl J Med 1998;339:245-253. PMID:9673304

  • Matzdorff A, Arnold G.
    Treatment of chronic immune thrombocytopenic purpura: the patients' perspective.
    Eur J Haematol 2007;78:381-388. PMID:17331128

  • Matzdorff A, Giagounidis A, Greinacher A, Hiller E, Kiefel V, Müller-Beißenhirtz H, Ostermann H, Rummel M, Sachs UJ, Salama A.
    Diagnostik und Therapie der mmunthrombozytopenie. Empfehlungen einer gemeinsamen Expertengruppe der DGHO, DGTI und GTH.
    Onkologie 2010;33(suppl 3):2-20. PMID:20484949
    http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000290758 [zitiert 15.03.2011]

  • McFarland JG, Collins J, Aster RH, Moghaddam M, Bussel J.
    Evaluation of a platelet glycoprotein (GP) specific assay in the diagnosis of autoimmune thrombocytopenia.
    Blood 1999;94(Suppl1):15a.

  • McMillan R, Luiken GA, Levy R, Yelenosky R, Longmire RL.
    Antibody against megakaryocytes in idiopathic thrombocytopenic purpura.
    JAMA 1978;239:2460-2462. PMID:565830

  • McMillan R, Wang L, Tomer A, Nichol J, Pistillo J.
    Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP.
    Blood 2004;103:1364-1369. PMID:14576051

  • Medeot M, Zaja F, Vianelli N, Battista M, Baccarani M, Patriarca F, Soldano F, Isola M, De Luca S, Fanin R.
    Rituximab therapy in adult patients with relapsed or refractory ITP: long term follow-up results.
    Eur J Haematol 2008;81:165-169. PMID:18510702

  • Meyer O, Agaylan A, Kiesewetter H, Salama A.
    A novel antigen-specific capture assay for the detection of platelet antibodies and HPA-1a phenotyping.
    Vox Sang 2006;91:324-330. PMID:17105608

  • Michel M, Cooper N, Jean C, Frissora C, Bussel JB.
    Does Helicobater pylori initiate or perpetuate im¬mune thrombocytopenic purpura?
    Blood 2004;103:890-896. PMID:12920031

  • Miller AB, Hoogstraten B, Staquet M, Winkler A.
    Reporting results of cancer treatment.
    Cancer 1981;47:207-214. PMID:7459811

  • Miranda M, Reich L, Traynor A, Young J, papadopoulas E, Fishman M, Welles C, Burt RK.
    Cure of Evans syndrome (autoimmune hemolytic anemia and idiopathic thrombotic thrombocytopenia) by allogeneic hematopoietic stem cell transplantation.
    Blood 1999;94(Suppl1):384b.

  • Mueller-Eckhardt C, Kiefel V, Grubert A, Grubert A, Kroll H, Weisheit M, Schmidt S, Mueller-Eckhardt G, Santoso S.
    348 cases of suspected neonatal alloimmune thrombocytopenia.
    Lancet 1989;1:363-366. PMID:2563515

  • Najean Y, Rain JD, Billotey C.
    The site of destruction of autologous 111In-labelled platelets and the efficiency of splenectomy in children and adults with idiopathic thrombocyto-penic purpura: a study of 578 patients with 268 splenectomies.
    British Journal of Haematology 1997;97:547-550. PMID:9207397

  • Nakamura R, Huhn RD, Read EJ, Rick M, Leitman SF, Greene A, Gratwohl A, Young NS, Barrett AJ, Dunbar CE.
    Intensive immunosuppression with high-dose cyclophosphamide and autologous CD34+ selected hematopoietic cell support for chronic refractory autoimmune thrombocytopenia (AITP): interim report.
    Blood 1999;94(Suppl1): 646a.

  • National Cancer Institute.
    NCI Common Terminology Criteria for Adverse Events: CTCAE, version MedDRA v9.0
    http://www.cancer.gov [accessed Jan 2010]

  • Nenci GG, Agnelli G, De Cunto M, Gresele P.
    Infusion of vincristine-loaded platelets in acute ITP refractory to steroids: an alternative to splenectomy.
    Acta Haematol 1981;66:117-121. PMID:6794311

  • Neunert CE, Buchanan GR, Imbach P, Bolton-Maggs PH, Bennett CM, Neufeld EJ, Vesely SK, Adix L, Blanchette VS, Kühne T; Intercontinental Childhood ITP Study Group Registry II Participants.
    Severe hemorrhage in children with newly diagnosed immune thrombocytopenic purpura.
    Blood 2008;112:4003-4008. PMID:18698007

  • Newland A, Caulier MT, Kappers-Klunne M, Schipperus MR, Lefrere F, Zwaginga JJ, Christal J, Chen CF, Nichol JL.
    An openlabel, unit dose-finding study of AMG 531, a novel thrombopoiesis-stimulating peptibody, in patients with immune thrombocytopenic purpura.
    Br J Haematol 2006;135:547-553. PMID:17061981

  • Neylon AJ, Saunders PW, Howard MR, Proctor SJ, Taylor PR; Northern Region Haematology Group.
    Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population-based cohort of 245 patients.
    Br J Haematol 2003;122:966-974. PMID:12956768

  • [No authors listed]
    Paul Gottlieb Werlhof (1699-1767) Thrombocytopenic purpura (Editorial).
    JAMA 1968;206:2892. PMID:4881773

  • Nomura S, Dan K, Hotta T, Fujimura K, Ikeda Y.
    Effects of pegylated recombinant human megakaryocyte growth and development factor in patients with idiopathic thrombocytopenic purpura.
    Blood 2002;100:728-730. PMID:12091377

  • Noris P, Klersy C, Zecca M, Arcaini L, Pecci A, Melazzini F, Terulla V, Bozzi V, Ambaglio C, Passamonti F, Locatelli F, Balduini CL.
    Platelet size distinguishes between inherited macrothrombocytopenias and immune thrombocytopenia.
    J Thromb Haemost 2009;7:2131-2136. PMID:19740094

  • Olsson A, Andersson PO, Tengborn L, Wadenvik H.
    Serum from patients with chronic idiopathic thrombocytopenic purpura frequently affect the platelet function.
    Thromb Res 2002;107:135-139. PMID:12431479

  • Olsson B, Andersson PO, Jacobsson S, Carlsson L, Wadenvik H.
    Disturbed apoptosis of T-cells in patients with active idiopathic thrombocytopenic purpura.
    Thromb Haemost 2005;93:139-144. PMID:15630504

  • Olsson B, Andersson PO, Jernås M, Jacobsson S, Carlsson B, Carlsson LM, Wadenvik H.
    T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpur.
    Nat Med 2003;9:1123-1124. PMID:12937414

  • Olsson B, Ridell B, Carlsson L, Jacobsson S, Wadenvik H.
    Recruitment of T cells into bone marrow of ITP patients possibly due to elevated expression of VLA-4 and CX3CR1.
    Blood 2008;112:1078-1084. PMID:18519809

  • Osterborg A, Karlsson C, Lundin J.
    Alemtuzumab to treat refractory autoimmune hemolytic anemia or thrombocytopenia in chronic lymphocytic leukemia.
    Curr Hematol Malig Rep 2009;4:47-53. PMID:20425438

  • Otton SH, Turner DL, Frewin R, Cavies SV, Johnson SA.
    Autoimmune thrombocytopenia after treatment with campath 1H in a patient with chronic lymphocytic leukaemia.
    Br J Haematol 1999;109: 261-262. PMID:10444204

  • Page LK, Psaila B, Provan D, Michael Hamilton J, Jenkins JM, Elish AS, Lesser ML, Bussel JB.
    The immune thrombocytopenic purpura (ITP) bleed¬ing score: assessment of bleeding in patients with ITP.
    Br J Haematol 2007;138:245-248. PMID:17542983

  • Pamma R, Deshpande M, Hokom M, Gupta S, Zhuang Y, Chirmule N, Swanson S, Jawa V.
    Impact Assessment of Immunogenicity of Romiplostim In Subjects with Immune Thrombocytopenic Purpura (ITP).
    Blood 2010;116(Suppl.):1043, Abstr. #2517.

  • Patel VL, Mahévas M, Stasi R, Cunningham-Rundles S, Godeau B, Lee SY, Kanter J, Neufeld EJ, Taube T, Ramenghi U, Shenoy S, Ward MJ, Mihatov N, Patel VL, Bierling P, Cooper N, Bussel JB.
    Long-Term Outcome Following B-Cell Depletion Therapy with Rituximab In Children and Adults with Immune Thrombocytopenia (ITP).
    Blood 2010;116(Suppl.):38, Abstr. #72.

  • Perotta A, Abduel C.
    Response of chronic relapsing ITP of 10 years duration to rituximab.
    Blood 1998;92(Suppl):88b.

  • Peterson LC, Rao KV, Crosson JT, White JG.
    Fechtner syndrome - a variant of Alports syndrome with leukocyte inclusions and macrothrombocytopenia.
    Blood 1985;65:397-406. PMID:2981587

  • Pizzuto J, Ambriz R.
    Therapeutic experience on 934 adults with idiopathic thrombocytopenic purpura: Multicentric Trial of the Cooperative Latin American Group on Hemostasis and Thrombosis.
    Blood 1984;64:1179-1183. PMID:6388663

  • Porcelijn L, Folman C.
    The diagnostic value of thrombopoietin level measurements in thrombocytopenia.
    Thromb Haemost 1998;79:1101-1105. PMID:9657431

  • Portielje JEA, Westendorp RGJ, Kluin-Nelemans HC, Brand A.
    Morbidity and mortality in adults with idiopathic thrombocytopenic purpura.
    Blood 2001;97:2549-2554. PMID:11313240

  • Provan D, Butler T, Evangelista ML, Amadori S, Newland AC, Stasi R.
    Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults.
    Haematologica 2007;92:1695-1698. PMID:18055995

  • Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, Chong BH, Cines DB, Gernsheimer TB, Godeau B, Grainger J, Greer I, Hunt BJ, Imbach PA, Lyons G, McMillan R, Rodeghiero F, Sanz MA, Tarantino M, Watson S, Young J, Kuter DJ.
    International consensus report on the investigation and management of primary immune thrombocytopenia.
    Blood 2010;115;168-196. PMID:19846889

  • Psaila B, Petrovic A, Page LK, Menell J, Schonholz M, Bussel JB.
    Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases.
    Blood 2009;114:4777-4783. PMID:19767509

  • Rault R, Piraino B, Johnston JR, Oral A.
    Pulmonary and renal toxicity of intravenous immunoglobulin.
    Clin Nephrol 1991;36:83-86. PMID:1934664

  • Rath W.
    Das HELLP-Syndrom - eine interdisziplinäre Herausforderung.
    Deutsch Ärztebl 1998;95:A-2997-3002.

  • Reese JA, Li X, Hauben M, Aster RH.
    Identifying drugs that cause acute thrombocytopenia: an analysis using 3 distinct methods.
    Blood 2010;116:2127-2133. PMID:20530792

  • Renaudier Ph, Beley O, Adeleine P, Treille-Ritouet D, Fiere D
    Diagnosis of idiopathic thrombopenic purpura (ITP): application of the ASHs guideline in 308 adult patients.
    Blood 1998;92(Suppl1):88b.

  • Rinder HM, Tracey JB, Recht M, DeCastro L, Rinder CS, McHugh C, Smith BR.
    Differences in platelet alpha-granule release between normals and immune thrombocytopenic patients and between young and old platelets.
    Thromb Haemos 1998;80:457-462. PMID:9759627

  • Rischewski JR, Imbach P, Paulussen M, Kühne T.
    Idiopathic thrombocytopenic purpura (ITP): is there a genetic predisposition?
    Pediatr Blood Cancer 2006;47(5Suppl):678-680. PMID:16933243

  • Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, Bussel JB, Cines DB, Chong BH, Cooper N, Godeau B, Lechner K, Mazzucconi MG, McMillan R, Sanz MA, Imbach P, Blanchette V, Kühne T, Ruggeri M, George JN.
    Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: Report from an International Working Group.
    Blood 2009;113:2386-2393. PMID:19005182

  • Rossi G, Cattaneo C, Motta M, Pizzocaro C, Lanzi S, Pouchè A.
    Platelet kinetic study in patients with idiopathic thrombocytopenic purpura (ITP) refractory or relapsing after corticosteroid treatment.
    Hematol J 2002;3:148-152. PMID:12111651

  • Ruggeri M, Castaman G, De Nardi G, Rodeghiero F.
    Acute renal failure after high-dose intravenous immune globulin in a patient with idiopathic thrombocytopenic purpura.
    Haematologica 1993;78:338-339. PMID:8314166

  • Sailer T, Lechner K, Panzer S, Kyrle PA, Pabinger I.
    The course of severe autoimmune thrombocytopenia in patients not undergoing splenectomy.
    Haematologica 2006;91:1041-1045. PMID:16885043

  • Salama A, Kiesewetter H, Kalus U, Movassaghi K, Meyer O.
    Massive platelet transfusion is a rapidly effective emergency treatment in patients with refractory autoimmune thrombocytopenia.
    Thromb Haemost 2008;100:762-765. PMID:18989518

  • Salama A, Rieke M, Kiesewetter H, von Depka M.
    Experiences with recombinant FVIIa in the emergency treatment of patients with autoimmune thrombocytopenia: a review of the literature.
    Ann Hematol 2009;88:11-15. PMID:18787824

  • Saleh MN, Cheng G, Bussel JB, Sun H, Mayer B, Bailey C, Brainsky A.
    EXTEND Study Update: Safety and Efficacy of Eltrombopag In Adults with Chronic Immune Thrombocytopenia (ITP) From June 2006 to February 2010.
    Blood 2010;116(Suppl.):36, Abstr. #67.

  • Samama CM, Djoudi R, Lecompte T, Nathan-Denizot N, Schved JF; Agence Française de Sécurité Sanitaire des Produits de Santé expert group.
    Perioperative platelet transfusion: recommendations of the Agence Francaise de Securite Sanitaire des Produits de Sante (AFSSaPS) 2003.
    Can J Anaesth 2005;52:30-37. PMID:15625253

  • Samuels P, Bussel JB, Braitman LE, Tomaski A, Druzin ML, Mennuti MT, Cines DB.
    Estimation of the risk of thrombocytopenia in the offspring of pregnant women with presumed immune thrombocytopenic purpura.
    N Engl J Med 1990;323:229-235. PMID:2366833

  • Sánchez Fayos J, Olavarría E, Román A, Cabello A, Soto C, Paniagua C.
    Idiopathic thrombocytopenic purpura in 5 members of a family.
    Sangre (Barc) 1994;39:215-217. PMID:7940053

  • Sarpatwari A, Bennett D, Logie JW, Shukla A, Beach KJ, Newland AC, Sanderson S, Provan D.
    Thromboembolic events among adult patients with primary immune thrombocytopenia (ITP) in the United Kingdom General Practice Research Database.
    Haematologica 2010a;95:1167-1175. PMID:20145266

  • Sarpatwari A, Provan D, Erqou S, Sobnack R, David Tai FW, Newland AC.
    Autologous 111 In-labelled platelet sequestration studies in patients with primary immune thrombocytopenia (ITP) prior to splenectomy: a report from the United Kingdom ITP Registry.
    Br J Haematol 2010b;151:477-487. PMID:20950403

  • Schiavotto C, Castaman G, Rodeghiero F.
    Treatment of idiopathic thrombocytopenic purpura (ITP) in patients with refractoriness to or with contraindication for corticoster¬oids and/or splenectomy with immunosuppressive therapy and danazol.
    Haematologica 1993;78 (Suppl 2):29-34. PMID:8039755

  • Schiavotto C, Ruggeri M, Rodeghiero F.
    Failure of repeated courses of high-dose intravenous immunoglobulin to induce stable remission in patients with chronic idiopathic thrombocytopenic purpura.
    Ann Hematol 1995;70:89-90. PMID:7880930

  • Schiebe ME, Hoffmann W, Belka C, Bamberg M.
    Mitomycin C-related hemolytic uremic syndrome in cancer patients.
    Anticancer Drug 1998;9:433-435. PMID:9660541

  • Schilling RF.
    Estimating the risk for sepsis after splenectom in hereditary spherocytosis.
    Ann Intern Med 1995;122:187-188. PMID:7810936

  • Schneemilch M, Mohren M, Fahlke J, et al.
    Thromboembolic complications after splenectomy: a rare but serious complication.
    Onkologie 2008;31 (Suppl4):194, Abstr. V561.

  • Schoonen WM, Kucera G, Coalson J, Li L, Rutstein M, Mowat F, Fryzek J, Kaye JA.
    Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database.
    Br J Haematol 2009a;145:235-244. PMID:19245432

  • Schoonen WM, Li L, Fryzek JP, Kaye JA.
    Medical contraindications for splenectomy among adults with immune thrombocytopenic purpura: data from the general parctice research database
    Haematologica 2009b;94(s2):96, Abstr. #0244

  • Schwartz J, Spitalnik S, Grima KM.
    Severe hemolysis following administration of Rho(D) immune globulin in an ITP patient associated with anti-C.
    Blood 2006;107:2585. PMID:16517982

  • Segal JB, Powe NR.
    Prevalence of immune thrombocytopenia: analyses of administrative data.
    J Thromb Haemost 2006;4:2377-2383. PMID:16869934

  • Semple JW.
    ITP three R's: regulation, routing, rituximab
    Blood 2008;112;927-928. PMID:18684874

  • Shibuya K, Akahori H, Tahara E, Kato T, Miyazaki H.
    Pegylated recombinant human megakaryocyte growth and development factor effectively improves thrombocytopenia in a murine model of idiopathic thrombocytopenic purpura, (NZW x BXSB)F1.
    Blood 1998;92(Suppl1):376a.

  • Shulman NR, Leissinger CA, Hotchkiss AJ, Kautz JA.
    The nonspecific nature of platelet-associated IgG.
    Trans Assoc Am Phys 1982;95:213-220. PMID:6985104

  • Shulman NR, Marder VJ, Weinrach RS.
    Similarities between known antiplatelet antibodies and the factor responsible for thrombocytopenia in idiopathic purpura. Physiologic, serologic and isotopic studies.
    Ann NY Acad Sci 1965;124:499-542. PMID:5214832

  • Siegel RS, Rae JL, Barth S, Coleman RE, Reba RC, Kurlander R, Rosse WF.
    Platelet survival and turnover: important factors in predicting response to splenectomy in immune thrombocytopenic purpura.
    Am J Hematol 1989;30:206-212. PMID:2929581

  • Simanek R, Panzer S, Lechner K, Pabinger I.
    Late spontaneous remissions in severe adult autoimmune thrombocytopenia.
    Ann Hematol 2007;86:705-710. PMID:17503045

  • Stasi R.
    Helicobacter pylori and chronic ITP.
    Hematology Am Soc Hematol Educ Program 2008a:206-211. PMID:19074084

  • Stasi R, Cooper N, Del Poeta G, Stipa , Laura Evangelista , Abruzzese , Amadori S.
    Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell-depleting therapy with ri¬tuximab.
    Blood 2008b;112:1147-1150. PMID:18375792

  • Stasi R, Sarpatwari A, Segal JB, Osborn J, Evangelista ML, Cooper N, Provan D, Newland A, Amadori S, Bussel JB.
    Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review.
    Blood 2009:113:1231-1240. PMID:18945961

  • Stasi R, Stipa E, Forte V, Meo P, Amadori S.
    Variable patterns of response to rituximab treatment in adults with chronic idiopathic thrombocytopenic purpura.
    Blood 2002;99:3872-3873. PMID:12014370

  • Stasi R, Stipa E, Masi M, Cecconi M, Scimo MT, Oliva F, Sciarra A, Perrotti AP, Adomo G, Amadori S.
    Long-term observation of 208 adults with chronic idiopathic thrombocytopenic purpura.
    Am J Med 1995;98:436-442. PMID:7733121

  • STIKO.
    Empfehlungen der Ständigen Impfkommission (STIKO) am Robert Koch-Institut/Stand: Juli 2010.
    www.rki.de [zitiert 15.03.2011]

  • Strupp C, Dietze L, Gattermann N, Germing U, Meckenstock G, Aul C.
    Severe autoimmune thrombocytopenia after fludarabine tratment in two patients with CLL.
    Onkolgie 1999;22(Suppl1):55.

  • Sullivan KE, Mullen CA, Blaese RM, Winkelstein JA.
    A multiinstitutional survey of the Wiskott-Aldrich syndrome.
    J Pediatr 1994;125: 876-885. PMID:7996359

  • Takahashi R, Sekine N, Nakatake T.
    Influence of monoclonal antiplatelet glycoprotein antibodies on in vitro human megakaryocyte colony fomration and proplatelet formation.
    Blood 1999;93:1951-1958. PMID:10068668

  • Thachil J, Callaghan T, Martlew V.
    Thromboembolic events are not uncommon in patients with immune thrombocytopenia.
    Br J Haematol 2010;150:496-497. PMID:20507305

  • Thomsen RW, Schoonen WM, Farkas DK, Riis A, Fryzek JP, Sørensen HT.
    Risk of venous thromboembolism in splenectomized patients compared with the general population and appendectomized patients: a 10-year nationwide cohort study.
    J Thromb Haemost 2010;8:1413-1416. PMID:20218983

  • van Loghem JJ, Dorfmeijer H, van der Hart M, Schreuder F.
    Serological and genetical studies on a platelet antigen (Zw).
    Vox Sang 1959;4:161-169. PMID:13669430

  • Verwey J, Breed WPM, Hilen HFP.
    Bleomycin-induced early-onset transient decrease in platelet counts.
    Neth J Med 1984;27:202-205. PMID:6205282

  • Vianelli N, Valdrè L, Fiacchini M, de Vivo A, Gugliotta L, Catani L, Lemoli RM, Poli M, Tura S.
    Long-term follow-up of idiopathic thrombocytopenic purpura in 310 patients.
    Haematologica 2001;86:504-509. PMID:11410414

  • von dem Borne AE, Helmerhorst FM, Leeuwen EF.
    Autoimmune thrombocytopenia: detection of platlet autoantibodies with a suspension immunofluorescence Test.
    Br J Haematol 1980;45:319-327. PMID:7002200

  • Warkentin TE, Greinacher A, Koster A, Lincoff AM; American College of Chest Physicians.
    Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
    Chest 2008;133(6Suppl):340S-380S. PMID:18574270

  • Warner M, Wasi P, Couban S, Hayward C, Warkentin T, Kelton JG.
    Failure of pulse high-dose desamethasone in chronic idiopathic immune thrombocytopenia.
    Am J Hematol 1997;54:267-270. PMID:9092679

  • Watson DI, Coventry BJ, Chin T, Gill PG, Malycha P.
    Laparoscopic versus open splenectomy for immune thrombocytopenic purpura.
    Surgery 1997;121:18-22. PMID:9001546

  • Weigert O, Wittmann G, Gruetzner S, Cnossen J, Becker MC, Dreyling M, Ostermann H.
    Vincristine-loaded platelets for immune thrombocytopenia.
    Thromb Haemost 2010;104(2):418-9. PMID:20508905

  • Weinmann M, Becker G, Einsele H, Bamberg M.
    Clinical indications and biological mechanisms of splenic irradiation in autoimmune diseases.
    Strahlenther Onkol 2001;177:105-111. PMID:11233832

  • Weisberger AS, Suhrland LG.
    Massive corticosteroid therapy in the management of resistant thrombocytopenic purpura.
    Am J Med Sci 1958;236:425-433. PMID:13582935

  • Westerman DA, Grigg AP.
    The diagnosis of idiopathic thrombocytopenic purpura in adults: does bone marrow biopsy have a place?
    Med J Aust 1999;170:216-217. PMID:10092918

  • Werlhof PG.
    Opera omnia. Hanover, Helwing, 748, 1775
    In Major RH, (ed.).
    Classic Descriptions of Disease, 3rd Edn.
    Springfield, IL, CC Thomas, 1965

  • Willan R.
    On Cutaneous Diseases.
    London, Barnard JG, 1808;452-471.

  • Willis F, Marsh JC, Bevan DH, Killick SB, Lucas G, Griffiths R, Ouwehand W, Hale G, Waldmann H, Gordon-Smith EC.
    The effect of treatment with Campath-1H in patients with autoimmune cytopenias.
    Br J Haematol 2001;114:891-898. PMID:11564082

  • Woodruff RK, Grigg AP, Firkin FC, Smith IL.
    Fatal thrombotic events during treatment of autoimmune thrombocytopenia with intravenous immunoglobulin in elderly patients.
    Lancet 1986;2(8500):217-218. PMID:2873457

  • Working Party of the British Committee for Standards in Haematology Clinical Haematology Task Force.
    Guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen.
    BMJ 1996;312:430-434. PMID:8601117

  • Yang C, Xia Y, Li J, Kuter DJ
    The appearance of anti-thrombopoietin antibody and circulating thrombopoietin-IgG complexes in a pateints developint thrombocytopenia after injection of PEG-rHuMGDF.
    Blood 1999;94(Suppl1):681a. PMID:

  • Yanabu M, Suzuki M, Soga T, Sone N, Nagata H, Nomura S, Kokawa T, Yasunaga K.
    Influences of antiplatelet autoantibodies on platelet function in immune thrombocytopenic purpura.
    Eur J Haematol 1991;46:101-106. PMID:1995321

  • Yu J, Heck S, Patel V, Levan J, Yu Y, Bussel JB, Yazdanbakhsh K.
    Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura.
    Blood 2008;112:1325-1328. PMID:18420827

  • Zhang W, Nardi MA, Borkowsky W, Li Z, Karpatkin S.
    Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia.
    Blood 2009;113:4086-4093. PMID:19023115

  • Zaja F, Baccarani M, Mazza P, Bocchia M, Gugliotta L, Zaccaria A, Vianelli N, Defina M, Tieghi A, Amadori S, Campagna S, Ferrara F, Angelucci E, Usala E, Cantoni S, Visani G, Fornaro A, Rizzi R, De Stefano V, Casulli F, Battista ML, Isola M, Soldano F, Gamba E, Fanin R.
    Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia.
    Blood 2010;115:2755-2762. PMID:20130241

  • Zwaginga JJ, van der Holt R, Biemond BJ, te Boekhorst PAW, Levin M, Vreughdenhil A, Huijgens PC, Brand A, van der Griend R, Luten M, Pruijt H, de Weerdt O, van Pampus E, Zweegman S, Hollestein R, Koene HR.
    Interim Analysis on a Dutch HOVON Multicenter Randomized Open Label Phase II Trial on 3 Rituximab Dosing Schemes In chronic ITP Patients.
    Blood 2010;116(Suppl):1042, Abstr. #2514.

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